TRANSFAC Site Quality Scores

Quality scores, ranging from 1 to 6, reflect the experimental reliability of a particular protein-DNA or miRNA-RNA interaction. These scores and their meanings are described in the table below.

Experimental Reliability of
Transcription Factor - Binding Site Interactions
or miRNA - Target Site Interactions

Score Meaning
1 Functionally confirmed transcription factor or miRNA binding site
2 Binding of pure protein or miRNA (purified or recombinant)
3 Immunologically characterized binding activity of a cellular extract
4 Binding activity characterized via a known binding sequence
5 Binding of uncharacterized extract protein to a bona fide element
6 No quality assigned

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