Introduction to the BIOBASE Knowledge Library
Welcome to the BIOBASE Knowledge Library (BKL), a fully integrated portfolio of scientific databases, tools, and services that help scientists answer complex biological questions of interest to their research. We offer our customers well-structured data, assembled by subject matter experts and organized in an accessible and easily searchable manner that enables them to identify connections between disparate pieces of information and to apply that knowledge to their specific topic of interest.
Components of the BKL
The BKL comprises two modules which are described below:
Proteome™ Module containing the HumanPSD and TRANSPATH databasesThe Proteome module comprises the most comprehensive collection
of protein information available across a broad range of species
including human, mouse, rat, yeast, worm, and plant. The module
features detailed, manual curation of the scientific literature,
comprehensive reference sets, disease information (for human
entries only), information about signaling cascades from TRANSPATH,
and our proprietary BioKnowledge Transfer (BKT) that process that predicts
functions and roles for previously uncharacterized proteins. |
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TRANSFAC ModuleTRANSFAC is the premier information source for gene-regulatory
correlations. The module features manually curated data on
transcription factors, their experimentally-determined binding
sites, the genes they regulate, and associations with human disease
derived from HumanPSD. In addition, TRANSFAC's broad compilation of
binding sites allows the derivation of positional weight matrices
for use in predicting additional transcription factor binding
sites. |