TRANSPATH Quality Matrix

Combinations of experimental materials and methods are given a reliability score, as shown in the TRANSPATH Quality Matrix below.

	A1-A5	B1-B3	B4	C1	D1	D2	E1	F1-F2	X1	X2
M1	6	6	6	6	6	6	2	6	6	6
M2	6	6	6	6	6	5	5	5	5	5
M3	2	3	3	3	3	4	4	6	6	3
M4	1	2	2	2	2	3	4	5	5	3
M5	2	2	3	3	4	4	4	5	5	3
M6	3	3	3	3	3	3	3	4	4	6
M7	3	3	3	3	4	4	4	5	5	6
M8	3	3	4	4	4	5	5	5	5	6
M9	4	4	4	4	4	4	4	4	4	6
M10	2	2	3	3	3	4	5	5	5	6
M11	4	4	4	4	4	4	4	4	4	6
M12	3	3	3	3	3	4	4	4	4	6
M13	2	2	2	2	3	4	4	5	5	6
M14	3	3	3	3	3	4	5	5	5	3
M15	3	3	3	3	3	3	4	5	5	6
M16	3	3	3	3	3	4	4	5	5	6
M17	6	3	3	3	3	3	3	4	4	6
M18	2	2	2	2	2	3	3	3	3	6
M19	3	3	4	4	4	4	4	5	5	6
M20	2	6	6	6	6	6	6	6	6	6
M21	4	4	4	4	4	4	4	6	6	6
M22	6	6	6	6	1	2	6	6	6	6
M23	3	3	3	3	3	4	4	5	5	3
M24	3	3	3	3	3	4	4	5	5	6
M25	2	2	2	2	3	3	4	5	5	3
M26	4	4	4	4	5	6	6	6	6	6
M27	3	3	3	4	4	4	4	4	5	6
M28*	6	6	6	6	6	6	6	6	6	6
M29*	2	3	3	3	3	4	4	6	6	6
M30*	3	3	4	4	4	5	5	5	5	3
M31*	6	6	6	6	6	6	6	6	6	6
M32*	6	3	3	3	3	4	6	6	6	6
M33*	2	2	3	3	4	4	4	5	5	6
M34*	6	6	6	6	6	6	6	6	6	3
M35*	3	3	3	3	3	4	4	4	4	3
M36*	6	6	6	6	6	6	6	6	6	6
M37*	1	2	2	2	2	3	4	5	5	6
M38*	4	4	4	4	4	4	4	4	4	6
M39*	6	6	6	6	6	6	6	6	6	6
M40*	6	6	6	6	6	6	6	6	6	6
M41*	6	6	6	6	6	6	6	6	6	6
M42*	3	3	3	3	4	4	4	5	5	6
M43*	6	6	6	6	6	6	6	6	6	6
M44*	6	6	6	6	2	6	6	6	6	6
M45	6	6	6	6	6	6	6	6	6	6
M46	6	6	6	6	6	6	6	6	6	6
M48	6	6	6	6	6	6	6	6	6	6
M49	6	6	6	6	6	6	6	6	6	6
M50	6	6	6	2	2	6	6	6	6	3
M51	6	6	6	6	6	6	6	6	6	6
M52	2	6	6	6	2	6	6	6	6	3
M53	6	6	6	6	2	6	6	6	6	3
M54	6	6	6	2	2	6	6	6	6	3
M55	6	6	6	2	2	6	6	6	6	3
M56	6	6	6	2	2	6	6	2	6	3
M57	6	6	6	6	2	6	6	6	6	3

* Methods were added in the course of integration of reactions from Proteome HumanPSD.

Biological material can be extracted from a complete organism, for example a knock-out mutant, or recombinant polypeptides. Thus, reactions obtained from experiments with different biological materials have different probabilities for existing in vivo. We provide a reliability score that is defined by each possible combination of category and method on a scale of 1 to 6, as described in the table below.

TRANSPATH Reliability Coding

Reliability Score	Reliability
1	Highest reliability
2	High reliability
3	Moderate (average) reliability
4	Modest reliability
5	Low reliability are provided.
6	Quality value not assigned