DNA Binding Domain Abbreviations in TRANSCompel

Abbreviation Meaning
C2H2 C2H2 zinc finger type: Sp1, YY1, Egr, RFLAT-1
C4 C4 zinc finger type of nuclear receptors: GR, PR, ER, RAR, T3R, VDR, COUP, HNF-4, SF-1
ETS HTH, Tryptophan clusters, ETS family
GATA C4 zinc finger GATA type
HLH bHLH (E2A, MyoD, myogenin), bHLH-ZIP (TFE3, USF, SREBP, c-Myc, AhR/Arnt, HIF-1, EBF)
HMG beta-Scaffold Factors with Minor Groove Contacts, HMGI(Y), Sox9
HOM HTH, homeo domain only (HNF-1, Pbx, Nkx), LIM-homeodomain (lmx-1), paired box (Pax), POU-domain (Oct, Pit)
HSH bHSH: AP-2
MADS beta-Scaffold Factors with Minor Groove Contacts, MADS box factors: MEF-2 and SRF families
MYB HTH, Tryptophan clusters, Myb family, HTH, Tryptophan clusters, IRF family
NF1 beta-Scaffold Factors with Minor Groove Contacts, Smad/NF-1, NF-1 factors
NFY beta-Scaffold Factors with Minor Groove Contacts, heteromeric CCAAT factors: NF-Y family
p53 beta-Scaffold Factors with Minor Groove Contacts, p53 family
REL beta-Scaffold Factors with Minor Groove Contacts, NF-kappaB and NF-AT families
RUNT beta-Scaffold Factors with Minor Groove Contacts, AML/PEBP family
SMAD beta-Scaffold Factors with Minor Groove Contacts, Smad/NF-1, SMAD family
STAT beta-Scaffold Factors with Minor Groove Contacts, STAT family
TEA HTH, TEA domain factors, TEF-1
UNCL DNA binding domain is unclassified (HAF, DPBF)
WH HTH, winged helix/fork head (HNF-3, E2F, FAST, RFX families)
ZIP bZIP, AP-1 family, ATF/CREB family, C/EBP family

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